Light and Sound Clears Amyloid in Alzheimer's
March 8, 2024 at 9:31 a.m.
An MIT news release by David Orenstein outlined the study's results, which showed that a flickering light and a gamma brain rhythm frequency of 40 hertz can reduce Alzheimer's disease (AD) progression and treat symptoms in human volunteers.
"MIT researchers reveal a key mechanism that may contribute to these beneficial effects: clearance of amyloid proteins, a hallmark of AD pathology, via the brain's glymphatic system, a recently discovered 'plumping' network parallel to the brain's blood vessels," writes Orenstein.
"We think that many neuropeptides are involved," said Mitch Murdock, PhD, who led the series of experiments for MIT's study. The scientists refer to the flickering lights and sounds at 40 hertz as sensory gamma stimulation. MIT reports that a major new direction for the lab's research will be determining what other peptides or molecular factors may be driving the clearance of amyloid proteins.
The studies at MIT and other research facilities are producing mounting evidence of the positive therapeutic benefits of non-invasive sensory, electrical or magnetic stimulation of gamma brain rhythms. With each new study, scientists are learning more about how stimulation of brain rhythms may help treat neurological disorders.
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